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apalutamide will minimize the level or effect of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Steer clear of or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP2C19 inducer, with medication which have been CYP2C19 substrates may end up in decreased exposure to these prescription drugs.Infants born to moms applying ben